Cardiovascular Revascularization Medicine
Volume 6, Issue 1 , Pages 38-43 , January 2005

Drug-eluting stents for the treatment of in-stent restenosis: A clinical review

  • Bryan P.Y. Yan

      Affiliations

    • Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia
    • Department of Epidemiology and Preventive Medicine, NHMRC Centre of Clinical Research Excellence in Therapeutics, Monash University, Melbourne, Australia
    • ,
  • Andrew E. Ajani

      Affiliations

    • Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia
    • Department of Epidemiology and Preventive Medicine, NHMRC Centre of Clinical Research Excellence in Therapeutics, Monash University, Melbourne, Australia
    • Corresponding Author InformationCorresponding author. Department of Cardiology, Royal Melbourne Hospital, Grattan Street, Parkville 3050, Australia. Tel.: +61 3 934 27000; fax: +61 3 934 72808.
    • ,
  • Ron Waksman

      Affiliations

    • Department of Cardiology, Washington Hospital Center, Washington, DC, United States

Received 14 April 2005 ,Accepted 18 April 2005.

References 

  1. Lowe HC, Oesterle SN, Khachigian LM. Coronary in-stent restenosis: current status and future strategies. J Am Coll Cardiol. 2002;39(2):183–193
  2. Radke PW, Kaiser A, Frost C, Sigwart U. Outcome after treatment of coronary in-stent restenosis; results from a systematic review using meta-analysis techniques. Eur Heart J. 2003;24(3):266–273
  3. Mehran R, Dangas G, Abizaid AS, Mintz GS, Lansky AJ, Satler LF, et al. Angiographic patterns of in-stent restenosis: classification and implications for long-term outcome. Circulation. 1999;100(18):1872–1878
  4. Waksman R, Bhargava B, White L, Chan RC, Mehran R, Lansky AJ, et al. Intracoronary beta-radiation therapy inhibits recurrence of in-stent restenosis. Circulation. 2000;101(16):1895–1898
  5. Waksman R, White RL, Chan RC, Bass BG, Geirlach L, Mintz GS, et al. Intracoronary gamma-radiation therapy after angioplasty inhibits recurrence in patients with in-stent restenosis. Circulation. 2000;101(18):2165–2171
  6. Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O'Shaughnessy C, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349(14):1315–1323
  7. Stone GW, Ellis SG, Cox DA, Hermiller J, O'Shaughnessy C, Mann JT, et al. A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med. 2004;350(3):221–331
  8. Hoffmann R, Mintz GS, Dussaillant GR, Popma JJ, Pichard AD, Satler LF, et al. Patterns and mechanisms of in-stent restenosis. A serial intravascular ultrasound study. Circulation. 1996;94(6):1247–1254
  9. Hong MK, Mintz GS, Lee CW, Song JM, Han KH, Kang DH, et al. Asian Paclitaxel-Eluting Stent Clinical Trial. Paclitaxel coating reduces in-stent intimal hyperplasia in human coronary arteries: a serial volumetric intravascular ultrasound analysis from the Asian Paclitaxel-Eluting Stent Clinical Trial (ASPECT). Circulation. 2003;107(4):517–520
  10. Sousa JE, Costa MA, Abizaid AC, Rensing BJ, Abizaid AS, Tanajura LF, et al. Sustained suppression of neointimal proliferation by sirolimus-eluting stents: one-year angiographic and intravascular ultrasound follow-up. Circulation. 2001;104(17):2007–2011
  11. Degertekin M, Regar E, Tanabe K, Smits PC, van der Giessen WJ, Carlier SG, et al. Sirolimus-eluting stent for treatment of complex in-stent restenosis: the first clinical experience. J Am Coll Cardiol. 2003;41(2):184–189
  12. Sousa JE, Costa MA, Abizaid A, Sousa AG, Feres F, Mattos LA, et al. Sirolimus-eluting stent for the treatment of in-stent restenosis: a quantitative coronary angiography and three-dimensional intravascular ultrasound study. Circulation. 2003;107(1):24–27
  13. Saia F, Lemos PA, Arampatzis CA, Hoye A, Degertekin M, Tanabe K, et al. Routine sirolimus eluting stent implantation for unselected in-stent restenosis: insights from the rapamycin eluting stent evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry. Heart. 2004;90(10):1183–1188
  14. Werner GS, Emig U, Krack A, Schwarz G, Figulla HR. Sirolimus-eluting stents for the prevention of restenosis in a worst-case scenario of diffuse and recurrent in-stent restenosis. Catheter Cardiovasc Interv. 2004;63(3):259–264
  15. Kastrati A, Mehilli J, von Beckerath N, Dibra A, Hausleiter J, Pache J, et al. Sirolimus-eluting stent or paclitaxel-eluting stent vs. balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: a randomized controlled trial. JAMA. 2005;293(2):165–171
  16. Iofina E, Haager PK, Radke PW, Langenberg R, Blindt R, Ortlepp J, et al. Sirolimus- and paclitaxel-eluting stents in comparison with balloon angioplasty for treatment of in-stent restenosis. Catheter Cardiovasc Interv. 2005;64(1):28
  17. Airoldi F, Rogacka R, Briguori C, Chieffo A, Carlino M, Montorfano M, et al. Comparison of clinical and angiographic outcome of sirolimus-eluting stent implantation versus cutting balloon angioplasty for coronary in-stent restenosis. Am J Cardiol. 2004;94(10):1297–1300
  18. Saia F, Lemos PA, Hoye A, Sianos G, Arampatzis CA, de Feyter PJ, et al. Clinical outcomes for sirolimus-eluting stent implantation and vascular brachytherapy for the treatment of in-stent restenosis. Catheter Cardiovasc Interv. 2004;62(3):283–288
  19. Radke PW, Kobella S, Kaiser A, Franke A, Schubert D, Grube E, et al. Treatment of in-stent restenosis using a paclitaxel-eluting stent: acute results and long-term follow-up of a matched-pair comparison with intracoronary beta-radiation therapy. Eur Heart J. 2004;25(11):920–925
  20. Leon MB, Teirstein PS, Moses JW, Tripuraneni P, Lansky AJ, Jani S, et al. Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting. N Engl J Med. 2001;344(4):250–256
  21. Liistro F, Stankovic G, Di Mario C, Takagi T, Chieffo A, Moshiri S, et al. First clinical experience with a paclitaxel derivate-eluting polymer stent system implantation for in-stent restenosis: immediate and long-term clinical and angiographic outcome. Circulation. 2002;105(16):1883–1886
  22. Tanabe K, Serruys PW, Grube E, Smits PC, Selbach G, van der Giessen WJ, et al. TAXUS III Trial: in-stent restenosis treated with stent-based delivery of paclitaxel incorporated in a slow-release polymer formulation. Circulation. 2003;107(4):559–564
  23. Ajani AE, Waksman R, Cheneau E, Cha DH, McGlynn S, Castagna M, et al. The outcome of percutaneous coronary intervention in patients with in-stent restenosis who failed intracoronary radiation therapy. J Am Coll Cardiol. 2003;41(4):551–556
  24. Waksman R, Lew R, Ajani AE, Pichard AD, Satler LF, Kent KM, et al. Repeat intracoronary radiation for recurrent in-stent restenosis in patients who failed intracoronary radiation. Circulation. 2003;108(6):654–656
  25. Saia F, Lemos PA, Sianos G, Degertekin M, Lee CH, Arampatzis CA, et al. Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy. Am J Cardiol. 2003;92(2):200–203
  26. Iakovou I, Sangiorgi GM, Stankovic G, Corvaja N, Michev I, Chieffo A, et al. Effectiveness of sirolimus-eluting stent implantation for treatment of in-stent restenosis after brachytherapy failure. Am J Cardiol. 2004;94(3):351–354
  27. Schiele TM, Rieber J, Konig A, Leibig M, Erhard I, Theisen K, et al. Comparison of acute and long-term results and underlying mechanisms from sirolimus-eluting stent implantation for the treatment of in-stent restenosis and recurrent in-stent restenosis in patients in whom intracoronary radiation failed as assessed by intravascular ultrasound. Am J Cardiol. 2004;94(7):917–921
  28. Colombo A, Orlic D, Stankovic G, Corvaja N, Spanos V, Montorfano M, et al. Preliminary observations regarding angiographic pattern of restenosis after rapamycin-eluting stent implantation. Circulation. 2003;107(17):2178–2180
  29. Lemos PA, Saia F, Ligthart JM, Arampatzis CA, Sianos G, Tanabe K, et al. Coronary restenosis after sirolimus-eluting stent implantation: morphological description and mechanistic analysis from a consecutive series of cases. Circulation. 2003;108(3):257–260
  30. Lemos PA, van Mieghem CA, Arampatzis CA, Hoye A, Ong AT, McFadden E, et al. Post-sirolimus-eluting stent restenosis treated with repeat percutaneous intervention: late angiographic and clinical outcomes. Circulation. 2004;109(21):2500–2502
  31. Fajadet J, Morice MC, Bode C, Barragan P, Serruys PW, Wijns W, et al. Maintenance of long-term clinical benefit with sirolimus-eluting coronary stents: three-year results of the RAVEL trial. Circulation. 2005;111(8):1040–1044

PII: S1553-8389(05)00034-5

doi: 10.1016/j.carrev.2005.04.003

Cardiovascular Revascularization Medicine
Volume 6, Issue 1 , Pages 38-43 , January 2005

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