Cardiovascular Revascularization Medicine
Volume 10, Issue 4 , Pages 229-235 , October 2009

Preliminary observations using optical coherence tomography to assess neointimal coverage of a metal stent in a porcine model

  • James S. Mills

      Affiliations

    • Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC, USA
    • Corresponding Author InformationCorresponding author. Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC 27710, USA. Tel.: +1 919 681 3763.
    • ,
  • Colleen Stack N'diaye

      Affiliations

    • Synecor, LLC, Durham, NC, USA
    • ,
  • Eric Yow

      Affiliations

    • Duke Clinical Research Institute, Durham, NC, USA
    • ,
  • Mark Urtz

      Affiliations

    • Synecor, LLC, Durham, NC, USA
    • ,
  • Thomas J. Povsic

      Affiliations

    • Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC, USA
    • ,
  • Joseph C. Greenfield

      Affiliations

    • Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC, USA
    • ,
  • Harry R. Phillips

      Affiliations

    • Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC, USA

Received 25 July 2008 ,Revised 3 November 2008 ,Accepted 4 November 2008.

References 

  1. Finn AV, Joner M, Nakazawa G, Kolodgie F, Newell J, John MC, et al. Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization. Circulation. 2007;115:2435–2441
  2. Joner M, Finn AV, Farb A, Mont EK, Kolodgie FD, Ladich E, et al. Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. J Am Coll Cardiol. 2006;48:193–202
  3. Prati F, Zimarino M, Stabile E, Pizzicannella G, Fouad T, Rabozzi R, et al. Does optical coherence tomography identify arterial healing after stenting? An in vivo comparison with histology, in a rabbit carotid model. Heart. 2008;94:217–221
  4. Matsumoto D, Shite J, Shinke T, Otake H, Tanino Y, Ogasawara D, et al. Neointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography. Eur Heart J. 2007;28:961–967
  5. Takano M, Inami S, Jang IK, Yamamoto M, Murakami D, Seimiya K, et al. Evaluation by optical coherence tomography of neointimal coverage of sirolimus-eluting stent three months after implantation. Am J Cardiol. 2007;99:1033–1038
  6. Abramoff M, Magelhaes P, Ram S. Image processing with ImageJ. Biophoton Int. 2004;11:36–42
  7. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307–310
  8. SAS Institute Inc . SAS/STAT® 8.0 User’s Guide. Cary, NC: SAS Institute Inc; 1999;
  9. Blindt R, Vogt F, Astafieva I, Fach C, Hristov M, Krott N, et al. A novel drug-eluting stent coated with an integrin-binding cyclic Arg-Gly-Asp peptide inhibits neointimal hyperplasia by recruiting endothelial progenitor cells. J Am Coll Cardiol. 2006;47:1786–1795
  10. Cho HJ, Kim TY, Cho HJ, Park KW, Zhang SY, Kim JH, et al. The effect of stem cell mobilization by granulocyte-colony stimulating factor on neointimal hyperplasia and endothelial healing after vascular injury with bare-metal versus paclitaxel-eluting stents. J Am Coll Cardiol. 2006;48:366–374
  11. Wilson GJ, Polovick JE, Huibregtse BA, Poff BC. Overlapping paclitaxel-eluting stents: long-term effects in a porcine coronary artery model. Cardiovasc Res. 2007;76:361–372
  12. Jang IK, Bouma BE, Kang DH, Park SJ, Park SW, Seung KB, et al. Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound. J Am Coll Cardiol. 2002;39:604–609
  13. Kotani J, Awata M, Nanto S, Uematsu M, Oshima F, Minamiguchi H, et al. Incomplete neointimal coverage of sirolimus-eluting stents: angioscopic findings. J Am Coll Cardiol. 2006;47:2108–2111
  14. Suzuki Y, Ikeno F, Koizumi T, Tio F, Yeung AC, Yock PG, et al. In vivo comparison between optical coherence tomography and intravascular ultrasound for detecting small degrees of in-stent neointima after stent implantation. J Am Coll Cardiol Intv. 2008;1:168–173

☆ Dr. Phillips is on the speaker's bureau for Boston Scientific. None of the other authors have financial disclosures relevant to the subject material.

PII: S1553-8389(08)00295-9

doi: 10.1016/j.carrev.2008.11.003

Cardiovascular Revascularization Medicine
Volume 10, Issue 4 , Pages 229-235 , October 2009

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